Body Composition

Understand weight loss, fat distribution and muscle composition in your clinical trials

Body composition analysis offers insights into the quality of weight loss and patient health. These powerful tools support decision-making in drug development across a broad spectrum of clinical trials (i.e. obesity, neuromuscular disorders, cancer cachexia).

It is time to look beyond weight…

Visceral fat
Ectopic fat
Muscle
Organ health

They all matter!

Relevant to support clinical trials in:

Obesity
Liver Disease
T2D
CVD
Muscular Dystrophy
Cancer Cachexia
Sarcopenia
Osteoporosis

Beyond BMI – Body Composition imaging is the new global standard in weight loss clinical trials

We provide neck-to-knee MRI body composition metrics including visceral (VAT) and subcutaneous adipose tissue (SAT), lean tissue volume, skeletal muscle volume and index, muscle fat infiltration (MFI), and suspected brown adipose tissue (sBAT).

Muscle volume and muscle fat infiltration – critical indicators of quality weight loss and overall health

Ectopic fat – impairs organ health and is one of major factors in cardiometabolic disease development

End-to-end imaging services

Our body composition analysis and organ health image offers insights into weight loss and patient health. These powerful tools support decision-making and trial design in drug development across a broader spectrum of clinical trials.

Our offering includes MRI body composition, MRI multi-organ ectopic fat and full-body DEXA assessment, which are fully customisable to your trial needs.

MRI body composition

Skeletal muscle
Visceral adipose tissue (VAT)
Subcutaneous adipose tissue (SAT)
Suspected brown adipose tissue (sBAT)
Muscle fat infiltration (MFI)

Multi-organ ectopic fat

Pericardial fat
Epicardial fat
Liver fat PDFF
Pancreatic fat PDFF
Peri-renal fat
Renal sinus fat

DXA / DEXA

Lean mass
Fat mass
Total mass
Percentage body fat
Bone mineral density (BMD)

Our expertise – your success in clinical trials

Global presence
Our technology is present in 900+ sites worldwide  

Regulatory and data privacy compliant

Seamless data integration and security

Rapid turnaround

In-house central platform 

180+ Publications

Scientific Publications


Original research publications:

  • Greater ectopic fat deposition and liver fibroinflammation and lower skeletal muscle mass in people with type 2diabetes – Obesity - Waddell et al
  • Single-sliceMRI for body composition assessment: repeatability, reproducibility, and observer variability – DiscoverImaging - Nowak et al
  • Poor glycaemic control and ectopic fat deposition mediates the increased risk of non-alcoholic steatohepatitis in high-risk populations in type 2 diabetes: Insights from Bayesian-network modelling – Front. Endocrinol. - Waddell et al
  • Bayesiannetworks and imaging-derived phenotypes highlight the role of fat deposition inCOVID-19 hospitalization risk – Front Bioinform - Waddell et al

Posters:

  • Fast and robust assessment of abdominal obesity in individuals with a range of cardiometabolic and liver tissue characteristics. (2024) [poster] AmericanDiabetes Association​ - Nowak et al
  • Quantitative multi-organ imaging stratifies individuals with obesity and diabetic retinopathy. (2024) [poster] American Diabetes Association​ – Diamond et al