Metrics

Liver Fat (MRI-PDFF)

Liver Stiffness (MRE)

Digital Pathology

Clinical Research Opportunity

     

Multi-Organ Characterization Comprehensive Patient Health

Expert central reads of quantitative metrics using our platform-based services for:

Liver, kidneys, pancreas, spleen, heart, aorta, biliary tree, colon, body composition and bone mineral density

Imaging Technologies include:

MRI, computerized tomography (CT), positron emission tomography (PET), DXA, endoscopy, and digital pathology.

Standardized and reproducible results

Our biomarkers have excellent reproducibility and repeatability7 with diagnostic accuracy that is superior to others. This enables more reliable monitoring of disease progression as a response to treatment and allows smaller trials to be run with more confidence. (19,20,21)


Our proprietary technology corrects for iron content, field strength, and manufacturer differences to deliver a “corrected T1” or cT1. This allows more robust metrics to be collected, thereby supporting multi-site trials.




References
  1. Banerjee, R., et al. (2014). J Hepatol, 60(1), 69-77. 
  2. Pavlides, M., et al. (2016). J Hepatol, 64(2), 308-315. 
  3. Pavlides, M., et al. (2017). Liver Int, 37(7), 1065-1073. 
  4. Idilman, I. S., et al. (2013). Radiology, 267(3), 767–775.
  5. Caussy, C., et al. (2018). Hepatology, 68(2), 763–772.
  6. Wilman, H.R., et al. (2017). PLOS ONE, 12(2), e0172921.
  7. Bachtiar, V., et al. (2019). PLOS ONE, 14(4), e0214921.
  8. McDonald, N., et al. (2018). Sci Rep, 8(1), 9189.
  9. Mayo R., et al. (2018). Hepatol Commun, 2(7), 807–20.
  10. Wildman-Tobriner, B., et al. (2018). Gastroenterology, 155(5), 1428–1435.
  11. Park, C. C., et al. (2017). Gastroenterology, 152(3), 598–607.
  12. Jayaswal, A., et al. (2020). Liver International, 40(12), 3071-3082.
  13. Dennis, A., et al. (2020). Scientific Reports, 10(1), 15308.
  14. Imajo, K., et al. (2021). World Journal of Gastroenterology, 27(7), 609–623.
  15. Dennis, A., et al. (2021). Frontiers in Endocrinology, 11, 575843.  
  16. Beyer, C., et al. (2021). Plos One, 16(4), e0249491.
  17. Andersson, A., et al. (2021). Clinical Gastroenterology and Hepatology, S1542-3565(21)01056-9.
  18. Harrison, S., et al. (2018). PloS One, 13(9), e0203054.
  19. Harrison, S.A. et al. (2020). Journal of Hepatology, 71(4), 1198–1212.
  20. Harrison, S.A., et al. (2021). The American Journal of Gastroenterology. 10.14309/ajg.0000000000001375
  21. Langford, C.R., et al. (2021). Journal of Clinical Pathology. 75(2), 73–75.

These products and services are for investigational use only.